Roles of Oncogenic Long Non-coding RNAs in Cancer Development
نویسندگان
چکیده
منابع مشابه
The Role of Long Non-Coding RNAs in Ovarian Cancer
Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. However, the aim of this review was to investigate the role of long non-co...
متن کاملThe Roles of Long non-coding RNAs (lncRNA) in Prostate Cancer
Background & Objective: Prostate cancer is a compound condition in which gene expression has altered. Several surveys have revealed that genetic components have been involved in prostate cancer progression. Findings proposed that they can modify a noteworthy portion of disposing of elements, which is associated to the developing prostate cancer in protein coding sequences. The purpose of this r...
متن کاملthe role of long non-coding rnas in ovarian cancer
background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...
متن کاملLong non-coding RNAs and their significance in human diseases
Protein-coding genes account for only a small fraction of the human genome and most of the genomic sequences are transcriptionally silent, but recent observations indicate significant functional elements, including non-coding protein transcripts in the human genome. Long non-coding RNAs (lncRNAs) have been defined as transcripts of >200 nucleotides without protein-coding capacity that perform t...
متن کاملThe regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer
Chemoresistance is one of the major hurdles in the treatment of breast cancer, which limits the effect of both targeted and conventional therapies in clinical settings. Therefore, understanding the mechanisms underpinning resistance is paramount for developing strategies to circumvent resistance in breast cancer patients. Several published reports have indicated that lncRNAs play a dynamic role...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genomics & Informatics
سال: 2018
ISSN: 2234-0742
DOI: 10.5808/gi.2018.16.4.e18